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Filtered by: 2014

Scientists Find 6 New Genetic Risk Factors for Parkinson's Disease

Sunday July 27, 2014

Using data from over 18,000 patients, scientists have identified more than two dozen genetic risk factors involved in Parkinson's disease, including six that had not been previously reported. The study, published in Nature Genetics, was partially funded by the National Institutes of Health (NIH) and led by scientists working in NIH laboratories.

"Unraveling the genetic underpinnings of Parkinson's is vital to understanding the multiple mechanisms involved in this complex disease, and hopefully, may one day lead to effective therapies," said Andrew Singleton, Ph.D., a scientist at the NIH's National Institute on Aging (NIA) and senior author of the study.

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Anti-inflammatory Drug Can Prevent Neuron Loss in Parkinson's Model

Friday July 25, 2014

An experimental anti-inflammatory drug can protect vulnerable neurons and reduce motor deficits in a rat model of Parkinson's disease, researchers at Emory University School of Medicine have shown.

The results were published in the Journal of Parkinson's Disease.

The findings demonstrate that the drug, called XPro1595, can reach the brain at sufficient levels and have beneficial effects when administered by subcutaneous injection, like an insulin shot. Previous studies of XPro1595 in animals tested more invasive modes of delivery, such as direct injection into the brain.

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New Drugs May Help With Parkinson’s Disease

Friday July 25, 2014

About 60,000 Americans are diagnosed with Parkinson’s disease each year. In 2010, the disease was responsible for the deaths of 22 Missouri residents between the ages of 65 and 74, and 169 Missouri residents over the age of 75, according to the Centers for Disease Control and Prevention.

Parkinson’s disease is a progressive disorder of the nervous system that affects your movement. It develops gradually, sometimes starting with a barely noticeable tremor in just one hand.

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StemGenex® Gives Hope to Parkinson’s Patients through New Stem Cell Clinical Study

Wednesday July 23, 2014

StemGenex®, the leading resource for adult adipose stem cell therapy in the US aimed at improving the lives of patients dealing with degenerative diseases today announced their newest clinical study for Parkinson’s disease. StemGenex believes that a commitment to the safety and efficacy of stem cell therapy are paramount when providing care to patients with degenerative diseases.

This clinical study makes stem cell therapy accessible to the millions of individuals currently living with Parkinson’s disease.

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Doctors Unravel The Placebo Effect Of Fake Parkinson's Disease Treatment

Friday July 18, 2014

In a new study examining patients with advanced Parkinson's disease, neurologists say they've identified parts of the brain that control placebo effect, raising hopes of singling out people most susceptible.

But they're still very much in the dark about underlying causes of one of medicine's great mysteries. Some people, when given fake treatment, actually get better, but others, for whatever reason, do not. Stranger still, some people improve at the mere suggestion of future treatment.

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Parkinson's Boosts Creativity: Study

Tuesday July 15, 2014

If you are in a creative profession, Parkinson's may be a blessing in disguise as researchers have found that patients of the nerve cells disease in the area of brain are more creative than their healthy peers.

Those Parkinson's patients taking higher doses of medication are more artistic than their less-medicated counterparts, the study added.

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How A Single Protein Could Unlock New Treatments For Brain Cancer And Parkinson's Disease

Tuesday July 15, 2014

The same protein that keeps neurons alive and healthy also gives cancer cells the longevity to grow and spread, a team of researchers said Tuesday.

The University of North Carolina announced the new findings, which are published in the journal Science Signaling, saying, "brain cancer cells hijack the same mechanism for their own survival." While the research could lead to breakthroughs in brain cancer, it also could provide fresh insight into the way Parkinson's disease destroys brain cells. Their results may spawn new treatment methods against the second most prevalent neurodegenerative disease, after Alzheimer's.

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Imaging Biomarker Proposed for Parkinson’s Disease

Thursday July 10, 2014

Reduced off-medication connectivity in the basal ganglia network (BGN) separates patients with early Parkinson’s disease (PD) from healthy controls with high accuracy, preliminary findings suggest.

Furthermore, the differences in BGN connectivity disappeared when the PD patients in the study were taking dopaminergic medication.

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Sleep Disturbances, Common in Parkinson's Disease, can be Early Indicator of Disease Onset

Thursday July 10, 2014

Up to 70% of Parkinson's disease (PD) patients experience sleep problems that negatively impact their quality of life. Some patients have disturbed sleep/wake patterns such as difficulty falling asleep or staying asleep, while other patients may be subject to sudden and involuntary daytime sleep "attacks." In the extreme, PD patients may exhibit REM-sleep behavior disorder (RBD), characterized by vivid, violent dreams or dream re-enactment, even before motor symptoms appear. A review in the Journal of Parkinson's Disease discusses the underlying causes of sleep problems in PD, as well as medications, disease pathology, and comorbidities, and describes the most appropriate diagnostic tools and treatment options.

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Cinnamon May be Used to Halt the Progression of Parkinson's Disease

Wednesday July 09, 2014

Neurological scientists at Rush University Medical Center have found that using cinnamon, a common food spice and flavoring material, can reverse the biomechanical, cellular and anatomical changes that occur in the brains of mice with Parkinson's disease (PD). The results of the study were recently published in the June 20 issue of the Journal of Neuroimmune Pharmacology.

"Cinnamon has been used widely as a spice throughout the world for centuries," said Kalipada Pahan, PhD, study lead researcher and the Floyd A. Davis professor of neurology at Rush. "This could potentially be one of the safest approaches to halt disease progression in Parkinson's patients."

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